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Regulation of ATP levels in Escherichia coli using CRISPR interference for enhanced pinocembrin production
BACKGROUND: Microbial biosynthesis of natural products holds promise for preclinical studies and treating diseases. For instance, pinocembrin is a natural flavonoid with important pharmacologic characteristics and is widely used in preclinical studies. However, high yield of natural products product...
Autores principales: | Tao, Sha, Qian, Ying, Wang, Xin, Cao, Weijia, Ma, Weichao, Chen, Kequan, Ouyang, Pingkai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142380/ https://www.ncbi.nlm.nih.gov/pubmed/30227873 http://dx.doi.org/10.1186/s12934-018-0995-7 |
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