Quantitative Vascular Evaluation: From Laboratory Experiments to Point-of-Care Patient (Clinical Approach)

To enhance the efficiency of patient-specific risk stratification and diagnosis, an assessment of arterial structural and functional changes associated to a vascular disease in both early and advanced stages have been proposed, with the objective of limiting the progression or revert vascular alterations. In this connection, an inter-disciplinary international partnership made up by research institutions from France, Argentina, Uruguay and Spain was es-tablished, with the objective of contributing to the evaluation and follow-up of factors involved in the physiopathology of cardiometabolic dis-eases and human aging. Several studies, such as the effect of hypertension in large arteries, alterations in arterial wall viscosi-ty, stiffness and inertia, endothelial function and vascular reactivity, cardiovascular risk improvement, vascular age assess-ment and cryografts vascular response evaluation were carried out as a result of this international collaboration during the last twenty-five years.