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Optimization and Validation of a Microscale In vitro Method to Assess α-Glucosidase Inhibition Activity
BACKGROUND: Microscale in vitro assays are fast, simple, and inexpensive, with reduced reagent quantities, waste, and experimental animal use. However, they have low reproducibility and low correlation with the results of in vivo models, possibly due to differences in precision and accuracy in metho...
Autores principales: | Granados-Guzmán, Graciela, Castro-Ríos, Rocío, Waksman de Torres, Noemí, Salazar-Aranda, Ricardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142409/ https://www.ncbi.nlm.nih.gov/pubmed/30294249 http://dx.doi.org/10.2174/1573411013666170911154755 |
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