The Development of New Factor Xa Inhibitors Based on Amide Synthesis

BACKGROUND: Factor Xa (FXa) is known to play a central role in blood coagulation cascade and considered to be one of the most attractive tar-gets for oral anticoagulants of new generation. OBJECTIVE: Our approach for the development of directly acting oral anticoagu-lants (DOAC), FXa inhibitors was...

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Detalles Bibliográficos
Autores principales: Tarasov, Dmitry N., Tovbin, Dmitry G., Malakhov, Dmitry V., Aybush, Arseniy V., Tserkovnikova, Natalia A., Savelyeva, Marina I., Sychev, Dmitry A., Drozd, Natalia N., Savchenko, Alla Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142410/
https://www.ncbi.nlm.nih.gov/pubmed/29468977
http://dx.doi.org/10.2174/1570163815666180215114732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142410/
https://www.ncbi.nlm.nih.gov/pubmed/29468977
http://dx.doi.org/10.2174/1570163815666180215114732

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