Increased inflammation, endoplasmic reticulum stress and oxidative stress in endothelial and macrophage cells exacerbate atherosclerosis in ApoCIII transgenic mice

BACKGROUND: Overexpression of apolipoprotein CIII (ApoCIII) leads to hypertriglyceridemia (HTG) which promotes atherosclerosis development. However, it remains unclear whether ApoCIII affects the atherosclerosis alone by promoting the inflammation and endoplasmic reticulum (ER) stress, or in combina...

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Detalles Bibliográficos
Autores principales: Yingchun, Han, Yahong, Ma, Jiangping, Wen, Xiaokui, He, Xiaohong, Zhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142424/
https://www.ncbi.nlm.nih.gov/pubmed/30223835
http://dx.doi.org/10.1186/s12944-018-0867-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142424/
https://www.ncbi.nlm.nih.gov/pubmed/30223835
http://dx.doi.org/10.1186/s12944-018-0867-5

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