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Bis(9)-(−)-Meptazinol, a novel dual-binding AChE inhibitor, rescues cognitive deficits and pathological changes in APP/PS1 transgenic mice

BACKGROUND: Alzheimer’s disease (AD) is a progressive and irreversible neurodegenerative brain disorder, which is the most common form of dementia. Intensive efforts have been made to find effective and safe treatment against AD. Acetylcholinesterase inhibitors (AChEIs) have been widely used for the...

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Detalles Bibliográficos
Autores principales:	Shi, Yuhuan, Huang, Wanying, Wang, Yu, Zhang, Rui, Hou, Lina, Xu, Jianrong, Qiu, Zhuibai, Xie, Qiong, Chen, Hongzhuan, Zhang, Yongfang, Wang, Hao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142624/ https://www.ncbi.nlm.nih.gov/pubmed/30237878 http://dx.doi.org/10.1186/s40035-018-0126-8

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