Catalyst-free synthesis of 4-acyl-NH-1,2,3-triazoles by water-mediated cycloaddition reactions of enaminones and tosyl azide

The synthesis of 4-acyl-NH-1,2,3-triazoles has been accomplished with high efficiency through the cycloaddition reactions between N,N-dimethylenaminones and tosyl azide. This method is featured with extraordinary sustainability by employing water as the sole medium, free of any catalyst or additive,...

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Autores principales: Yang, Lu, Wu, Yuwei, Yang, Yiming, Wen, Chengping, Wan, Jie-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2018
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142726/
https://www.ncbi.nlm.nih.gov/pubmed/30254699
http://dx.doi.org/10.3762/bjoc.14.210
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author Yang, Lu
Wu, Yuwei
Yang, Yiming
Wen, Chengping
Wan, Jie-Ping
author_facet Yang, Lu
Wu, Yuwei
Yang, Yiming
Wen, Chengping
Wan, Jie-Ping
author_sort Yang, Lu
collection PubMed
description The synthesis of 4-acyl-NH-1,2,3-triazoles has been accomplished with high efficiency through the cycloaddition reactions between N,N-dimethylenaminones and tosyl azide. This method is featured with extraordinary sustainability by employing water as the sole medium, free of any catalyst or additive, authentically mild conditions (40 °C stirring) as well as practical scalability.
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spelling pubmed-61427262018-09-25 Catalyst-free synthesis of 4-acyl-NH-1,2,3-triazoles by water-mediated cycloaddition reactions of enaminones and tosyl azide Yang, Lu Wu, Yuwei Yang, Yiming Wen, Chengping Wan, Jie-Ping Beilstein J Org Chem Full Research Paper The synthesis of 4-acyl-NH-1,2,3-triazoles has been accomplished with high efficiency through the cycloaddition reactions between N,N-dimethylenaminones and tosyl azide. This method is featured with extraordinary sustainability by employing water as the sole medium, free of any catalyst or additive, authentically mild conditions (40 °C stirring) as well as practical scalability. Beilstein-Institut 2018-09-07 /pmc/articles/PMC6142726/ /pubmed/30254699 http://dx.doi.org/10.3762/bjoc.14.210 Text en Copyright © 2018, Yang et al. https://creativecommons.org/licenses/by/4.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0). Please note that the reuse, redistribution and reproduction in particular requires that the authors and source are credited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Yang, Lu
Wu, Yuwei
Yang, Yiming
Wen, Chengping
Wan, Jie-Ping
Catalyst-free synthesis of 4-acyl-NH-1,2,3-triazoles by water-mediated cycloaddition reactions of enaminones and tosyl azide
title Catalyst-free synthesis of 4-acyl-NH-1,2,3-triazoles by water-mediated cycloaddition reactions of enaminones and tosyl azide
title_full Catalyst-free synthesis of 4-acyl-NH-1,2,3-triazoles by water-mediated cycloaddition reactions of enaminones and tosyl azide
title_fullStr Catalyst-free synthesis of 4-acyl-NH-1,2,3-triazoles by water-mediated cycloaddition reactions of enaminones and tosyl azide
title_full_unstemmed Catalyst-free synthesis of 4-acyl-NH-1,2,3-triazoles by water-mediated cycloaddition reactions of enaminones and tosyl azide
title_short Catalyst-free synthesis of 4-acyl-NH-1,2,3-triazoles by water-mediated cycloaddition reactions of enaminones and tosyl azide
title_sort catalyst-free synthesis of 4-acyl-nh-1,2,3-triazoles by water-mediated cycloaddition reactions of enaminones and tosyl azide
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142726/
https://www.ncbi.nlm.nih.gov/pubmed/30254699
http://dx.doi.org/10.3762/bjoc.14.210
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