The Role of Autoimmune Regulator (AIRE) in Peripheral Tolerance

Autoimmune regulator (AIRE), whose gene mutation is considered to be a causative factor of autoimmune polyglandular syndrome type 1 (APS1), is an important transcriptional regulator. Studies on the role of AIRE in the central immune system have demonstrated that AIRE can eliminate autoreactive T cel...

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Detalles Bibliográficos
Autores principales: Zhao, Bingjie, Chang, Lu, Fu, Haiying, Sun, Guangyu, Yang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142728/
https://www.ncbi.nlm.nih.gov/pubmed/30255105
http://dx.doi.org/10.1155/2018/3930750

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