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Synthesis of indolo[1,2-c]quinazolines from 2-alkynylaniline derivatives through Pd-catalyzed indole formation/cyclization with N,N-dimethylformamide dimethyl acetal

An efficient strategy for the synthesis of 6-unsubstituted indolo[1,2-c]quinazolines is described. The Pd-catalyzed reaction of o-(o-aminophenylethynyl) trifluoroacetanilides with Ar–B(OH)(2) afforded 2-(o-aminophenyl)-3-arylindoles, that were converted to 12-arylindolo[1,2-c]quinazolines by adding...

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Detalles Bibliográficos
Autores principales:	Arcadi, Antonio, Cacchi, Sandro, Fabrizi, Giancarlo, Ghirga, Francesca, Goggiamani, Antonella, Iazzetti, Antonia, Marinelli, Fabio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2018
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142776/ https://www.ncbi.nlm.nih.gov/pubmed/30254707 http://dx.doi.org/10.3762/bjoc.14.218

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