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Sialylated keratan sulfate proteoglycans are Siglec-8 ligands in human airways

Human siglecs are a family of 14 sialic acid-binding proteins, most of which are expressed on subsets of immune cells where they regulate immune responses. Siglec-8 is expressed selectively on human allergic inflammatory cells—primarily eosinophils and mast cells—where engagement causes eosinophil a...

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Detalles Bibliográficos
Autores principales: Gonzalez-Gil, Anabel, Porell, Ryan N, Fernandes, Steve M, Wei, Yadong, Yu, Huifeng, Carroll, Daniela J, McBride, Ryan, Paulson, James C, Tiemeyer, Michael, Aoki, Kazuhiro, Bochner, Bruce S, Schnaar, Ronald L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142871/
https://www.ncbi.nlm.nih.gov/pubmed/29924315
http://dx.doi.org/10.1093/glycob/cwy057