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Mutational landscape of a chemically-induced mouse model of liver cancer

BACKGROUND & AIMS: Carcinogen-induced mouse models of liver cancer are used extensively to study the pathogenesis of the disease and are critical for validating candidate therapeutics. These models can recapitulate molecular and histological features of human disease. However, it is not known if...

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Detalles Bibliográficos
Autores principales: Connor, Frances, Rayner, Tim F., Aitken, Sarah J., Feig, Christine, Lukk, Margus, Santoyo-Lopez, Javier, Odom, Duncan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142872/
https://www.ncbi.nlm.nih.gov/pubmed/29958939
http://dx.doi.org/10.1016/j.jhep.2018.06.009

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