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Complex Evolutionary History of Translation Elongation Factor 2 and Diphthamide Biosynthesis in Archaea and Parabasalids

Diphthamide is a modified histidine residue which is uniquely present in archaeal and eukaryotic elongation factor 2 (EF-2), an essential GTPase responsible for catalyzing the coordinated translocation of tRNA and mRNA through the ribosome. In part due to the role of diphthamide in maintaining trans...

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Detalles Bibliográficos
Autores principales:	Narrowe, Adrienne B, Spang, Anja, Stairs, Courtney W, Caceres, Eva F, Baker, Brett J, Miller, Christopher S, Ettema, Thijs J G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143161/ https://www.ncbi.nlm.nih.gov/pubmed/30060184 http://dx.doi.org/10.1093/gbe/evy154

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