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Frequent transmission of the Mycobacterium tuberculosis Beijing lineage and positive selection for EsxW Beijing variant in Vietnam
To examine transmission dynamics of Mtb isolated from TB patients in Ho Chi Minh City, Vietnam we sequenced whole genomes of 1,635 isolates and compared these with 3,144 isolates from elsewhere. The data reveal an underlying burden of disease caused by endemic Mtb Lineage 1 associated with activatio...
Autores principales: | Holt, Kathryn E, McAdam, Paul, Thai, Phan Vuong Khac, Thuong, Nguyen Thuy Thuong, Ha, Dang Thi Minh, Lan, Nguyen Ngoc, Lan, Nguyen Huu, Nhu, Nguyen Thi Quynh, Hai, Hoang Thanh, Ha, Vu Thi Ngoc, Thwaites, Guy, Edwards, David J, Nath, Artika P, Pham, Kym, Ascher, David B, Farrar, Jeremy, Khor, Chiea Chuen, Teo, Yik Ying, Inouye, Michael, Caws, Maxine, Dunstan, Sarah J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143168/ https://www.ncbi.nlm.nih.gov/pubmed/29785015 http://dx.doi.org/10.1038/s41588-018-0117-9 |
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