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Increased mortality in CD43-deficient mice during sepsis
CD43 is a large transmembrane protein involved in T cell activation. Previous studies of CD43(-/-) mice in viral models have demonstrated a role for CD43 in Th1/Th2 skewing, activation of Foxp3+ Treg, and T cell apoptosis. However, the role of CD43 during sepsis has never been tested. Thus, we inter...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143188/ https://www.ncbi.nlm.nih.gov/pubmed/30226896 http://dx.doi.org/10.1371/journal.pone.0202656 |