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Dual compartmental targeting of cell cycle and angiogenic kinases in colorectal cancer models

Cancer is a disease caused by several factors characterized by uncontrolled cell division, growth, and survival. ENMD-2076, is a novel orally active small molecule multikinase inhibitor targeting angiogenesis, proliferation, and the cell cycle. It is selectively active against the mitotic kinases au...

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Detalles Bibliográficos
Autores principales:	Capasso, Anna, Pitts, Todd M., Klauck, Peter J., Bagby, Stacey M., Westbrook, Lindsey, Kaplan, Jeffrey, Soleimani, Milad, Spreafico, Anna, Tentler, John J., Diamond, Jennifer R., Arcaroli, John J., Messersmith, Wells A., Eckhardt, Sue G., Leong, Stephen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2018
Materias:	Preclinical Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143222/ https://www.ncbi.nlm.nih.gov/pubmed/30048249 http://dx.doi.org/10.1097/CAD.0000000000000673

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