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Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal
Adaptive evolution in humans has rarely been characterized for its whole set of components, i.e. selective pressure, adaptive phenotype, beneficial alleles and realized fitness differential. We combined approaches for detecting polygenic adaptations and for mapping the genetic bases of physiological...
Autores principales: | Jeong, Choongwon, Witonsky, David B., Basnyat, Buddha, Neupane, Maniraj, Beall, Cynthia M., Childs, Geoff, Craig, Sienna R., Novembre, John, Di Rienzo, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143271/ https://www.ncbi.nlm.nih.gov/pubmed/30188897 http://dx.doi.org/10.1371/journal.pgen.1007650 |
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