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Protecting Encapsulin Nanoparticles with Cysteine-Knot Miniproteins
[Image: see text] A big hurdle for the use of protein-based drugs is that they are easily degraded by proteases in the human body. In an attempt to solve this problem, we show the possibility to functionalize TM encapsulin nanoparticles with an mEETI-II knottin miniprotein from the cysteine-stabiliz...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143317/ https://www.ncbi.nlm.nih.gov/pubmed/30047270 http://dx.doi.org/10.1021/acs.molpharmaceut.8b00630 |