An intrinsic cell cycle timer terminates limb bud outgrowth

The longstanding view of how proliferative outgrowth terminates following the patterning phase of limb development involves the breakdown of reciprocal extrinsic signalling between the distal mesenchyme and the overlying epithelium (e-m signalling). However, by grafting distal mesenchyme cells from...

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Detalles Bibliográficos
Autores principales: Pickering, Joseph, Rich, Constance A, Stainton, Holly, Aceituno, Cristina, Chinnaiya, Kavitha, Saiz-Lopez, Patricia, Ros, Marian A, Towers, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143340/
https://www.ncbi.nlm.nih.gov/pubmed/30175958
http://dx.doi.org/10.7554/eLife.37429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143340/
https://www.ncbi.nlm.nih.gov/pubmed/30175958
http://dx.doi.org/10.7554/eLife.37429

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