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An intrinsic cell cycle timer terminates limb bud outgrowth
The longstanding view of how proliferative outgrowth terminates following the patterning phase of limb development involves the breakdown of reciprocal extrinsic signalling between the distal mesenchyme and the overlying epithelium (e-m signalling). However, by grafting distal mesenchyme cells from...
Autores principales: | Pickering, Joseph, Rich, Constance A, Stainton, Holly, Aceituno, Cristina, Chinnaiya, Kavitha, Saiz-Lopez, Patricia, Ros, Marian A, Towers, Matthew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143340/ https://www.ncbi.nlm.nih.gov/pubmed/30175958 http://dx.doi.org/10.7554/eLife.37429 |
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