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Direct visualization of a native Wnt in vivo reveals that a long-range Wnt gradient forms by extracellular dispersal

Wnts are evolutionarily conserved signaling proteins with essential roles in development and disease that have often been thought to spread between cells and signal at a distance. However, recent studies have challenged this model, and whether long-distance extracellular Wnt dispersal occurs and is...

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Detalles Bibliográficos
Autores principales: Pani, Ariel M, Goldstein, Bob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143344/
https://www.ncbi.nlm.nih.gov/pubmed/30106379
http://dx.doi.org/10.7554/eLife.38325

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