A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells

RNAs directly regulate a vast array of cellular processes, emphasizing the need for robust approaches to fluorescently label and track RNAs in living cells. Here, we develop an RNA imaging platform using the cobalamin riboswitch as an RNA tag and a series of probes containing cobalamin as a fluoresc...

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Detalles Bibliográficos
Autores principales: Braselmann, Esther, Wierzba, Aleksandra J., Polaski, Jacob T., Chromiński, Mikołaj, Holmes, Zachariah E., Hung, Sheng-Ting, Batan, Dilara, Wheeler, Joshua R., Parker, Roy, Jimenez, Ralph, Gryko, Dorota, Batey, Robert T., Palmer, Amy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143402/
https://www.ncbi.nlm.nih.gov/pubmed/30061719
http://dx.doi.org/10.1038/s41589-018-0103-7

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