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Pkd2l1 is required for mechanoception in cerebrospinal fluid-contacting neurons and maintenance of spine curvature

Defects in cerebrospinal fluid (CSF) flow may contribute to idiopathic scoliosis. However, the mechanisms underlying detection of CSF flow in the central canal of the spinal cord are unknown. Here we demonstrate that CSF flows bidirectionally along the antero-posterior axis in the central canal of z...

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Detalles Bibliográficos
Autores principales:	Sternberg, Jenna R., Prendergast, Andrew E., Brosse, Lucie, Cantaut-Belarif, Yasmine, Thouvenin, Olivier, Orts-Del’Immagine, Adeline, Castillo, Laura, Djenoune, Lydia, Kurisu, Shusaku, McDearmid, Jonathan R., Bardet, Pierre-Luc, Boccara, Claude, Okamoto, Hitoshi, Delmas, Patrick, Wyart, Claire
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143598/ https://www.ncbi.nlm.nih.gov/pubmed/30228263 http://dx.doi.org/10.1038/s41467-018-06225-x

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