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A high content, small molecule screen identifies candidate molecular pathways that regulate rod photoreceptor outer segment renewal

The outer segment of the vertebrate rod photoreceptor is a highly modified cilium composed of many discrete membranous discs that are filled with the protein machinery necessary for phototransduction. The unique outer segment structure is renewed daily with growth at the base of the outer segment wh...

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Detalles Bibliográficos
Autores principales: Campbell, Leah J., West, Megan C., Jensen, Abbie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143611/
https://www.ncbi.nlm.nih.gov/pubmed/30228302
http://dx.doi.org/10.1038/s41598-018-32336-y