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Paf1 and Ctr9 subcomplex formation is essential for Paf1 complex assembly and functional regulation
The evolutionarily conserved multifunctional polymerase-associated factor 1 (Paf1) complex (Paf1C), which is composed of at least five subunits (Paf1, Leo1, Ctr9, Cdc73, and Rtf1), plays vital roles in gene regulation and has connections to development and human diseases. Here, we report two structu...
Autores principales: | Xie, Ying, Zheng, Minying, Chu, Xinlei, Chen, Yue, Xu, Huisha, Wang, Jiawei, Zhou, Hao, Long, Jiafu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143631/ https://www.ncbi.nlm.nih.gov/pubmed/30228257 http://dx.doi.org/10.1038/s41467-018-06237-7 |
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