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Paf1 and Ctr9 subcomplex formation is essential for Paf1 complex assembly and functional regulation

The evolutionarily conserved multifunctional polymerase-associated factor 1 (Paf1) complex (Paf1C), which is composed of at least five subunits (Paf1, Leo1, Ctr9, Cdc73, and Rtf1), plays vital roles in gene regulation and has connections to development and human diseases. Here, we report two structu...

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Detalles Bibliográficos
Autores principales: Xie, Ying, Zheng, Minying, Chu, Xinlei, Chen, Yue, Xu, Huisha, Wang, Jiawei, Zhou, Hao, Long, Jiafu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143631/
https://www.ncbi.nlm.nih.gov/pubmed/30228257
http://dx.doi.org/10.1038/s41467-018-06237-7

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