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Akt2 Regulates the Differentiation and Function of NKT17 Cells via FoxO-1-ICOS Axis

As a critical linker between mTORC1 and mTORC2, Akt is important for the cell metabolism. The role of Akt in the function and development of B and T cells is well characterized, however, the role of Akt for development and function of iNKT cells is unknown. iNKT cells bridge the adaptive and innate...

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Detalles Bibliográficos
Autores principales: Niu, LinLin, Xuan, Xingtian, Wang, Jinzhi, Li, Liling, Yang, Di, Jing, Yukai, Westerberg, Lisa S., Liu, Chaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143662/
https://www.ncbi.nlm.nih.gov/pubmed/30258434
http://dx.doi.org/10.3389/fimmu.2018.01940