Processing of DNA Ends in the Maintenance of Genome Stability

DNA double-strand breaks (DSBs) are particularly hazardous lesions as their inappropriate repair can result in chromosome rearrangements, an important driving force of tumorigenesis. DSBs can be repaired by end joining mechanisms or by homologous recombination (HR). HR requires the action of several...

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Detalles Bibliográficos
Autores principales: Bonetti, Diego, Colombo, Chiara Vittoria, Clerici, Michela, Longhese, Maria Pia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143663/
https://www.ncbi.nlm.nih.gov/pubmed/30258457
http://dx.doi.org/10.3389/fgene.2018.00390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143663/
https://www.ncbi.nlm.nih.gov/pubmed/30258457
http://dx.doi.org/10.3389/fgene.2018.00390

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