Interaction of Abl Tyrosine Kinases with SOCS3 Impairs Its Suppressor Function in Tumorigenesis()()()

Suppressor of cytokine signaling 3 (SOCS3) is involved in Bcr-Abl–induced tumorigenesis. However, how SOCS3 interacts with Bcr-Abl and is regulated by Abl kinases remains largely unknown. Since c-Abl plays a critical role in tumorigenesis, we asked whether SOCS3 is regulated by c-Abl–dependent phosp...

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Detalles Bibliográficos
Autores principales: Feng, Riyue, Wang, Xuefei, Li, Jianning, Chen, Ke, Guo, Guijie, Liao, Yuan, Sun, Liping, Huang, Shile, Chen, Ji-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143717/
https://www.ncbi.nlm.nih.gov/pubmed/30236924
http://dx.doi.org/10.1016/j.neo.2018.09.002

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