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Treatment of Human Glioblastoma with a Live Attenuated Zika Virus Vaccine Candidate

Glioblastoma (GBM) is the deadliest type of brain tumor, and glioma stem cells (GSCs) contribute to tumor recurrence and therapeutic resistance. Thus, an oncolytic virus targeting GSCs may be useful for improving GBM treatment. Because Zika virus (ZIKV) has an oncolytic tropism for infecting GSCs, w...

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Detalles Bibliográficos
Autores principales: Chen, Qi, Wu, Jin, Ye, Qing, Ma, Feng, Zhu, Qian, Wu, Yan, Shan, Chao, Xie, Xuping, Li, Dapei, Zhan, Xiaoyan, Li, Chunfeng, Li, Xiao-Feng, Qin, Xiaoling, Zhao, Tongyang, Wu, Haitao, Shi, Pei-Yong, Man, Jianghong, Qin, Cheng-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143740/
https://www.ncbi.nlm.nih.gov/pubmed/30228241
http://dx.doi.org/10.1128/mBio.01683-18