Transcriptomic data on the role of PEST-domain-enriched tyrosine phosphatase in the regulation of antigen-mediated activation and antiallergic action of glucocorticoids in mast cells

Protein tyrosine phosphatases and glucocorticoids are known to regulate allergic and antiallergic action in activated mast cells. Here we provide RNA sequencing and quantitative real-time PCR data from bone marrow derived mast cells, for wild-type and PEST-domain-enriched tyrosine phosphatase (PEP)...

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Autores principales: Ainooson, George K., Gourain, Victor, Stassen, Michael, Cato, Andrew C.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Energy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143756/
https://www.ncbi.nlm.nih.gov/pubmed/30238026
http://dx.doi.org/10.1016/j.dib.2018.08.188
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author Ainooson, George K.
Gourain, Victor
Stassen, Michael
Cato, Andrew C.B.
author_facet Ainooson, George K.
Gourain, Victor
Stassen, Michael
Cato, Andrew C.B.
author_sort Ainooson, George K.
collection PubMed
description Protein tyrosine phosphatases and glucocorticoids are known to regulate allergic and antiallergic action in activated mast cells. Here we provide RNA sequencing and quantitative real-time PCR data from bone marrow derived mast cells, for wild-type and PEST-domain-enriched tyrosine phosphatase (PEP) null mice, activated by immunoglobulin E sensitization and dinitrophenol treatment, and additionally treated with the glucocorticoid dexamethasone. The transcriptomics experiment was performed in duplicate with a total of 16 samples (GSE108972).
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spelling pubmed-61437562018-09-20 Transcriptomic data on the role of PEST-domain-enriched tyrosine phosphatase in the regulation of antigen-mediated activation and antiallergic action of glucocorticoids in mast cells Ainooson, George K. Gourain, Victor Stassen, Michael Cato, Andrew C.B. Data Brief Energy Protein tyrosine phosphatases and glucocorticoids are known to regulate allergic and antiallergic action in activated mast cells. Here we provide RNA sequencing and quantitative real-time PCR data from bone marrow derived mast cells, for wild-type and PEST-domain-enriched tyrosine phosphatase (PEP) null mice, activated by immunoglobulin E sensitization and dinitrophenol treatment, and additionally treated with the glucocorticoid dexamethasone. The transcriptomics experiment was performed in duplicate with a total of 16 samples (GSE108972). Elsevier 2018-09-05 /pmc/articles/PMC6143756/ /pubmed/30238026 http://dx.doi.org/10.1016/j.dib.2018.08.188 Text en © 2018 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Energy
Ainooson, George K.
Gourain, Victor
Stassen, Michael
Cato, Andrew C.B.
Transcriptomic data on the role of PEST-domain-enriched tyrosine phosphatase in the regulation of antigen-mediated activation and antiallergic action of glucocorticoids in mast cells
title Transcriptomic data on the role of PEST-domain-enriched tyrosine phosphatase in the regulation of antigen-mediated activation and antiallergic action of glucocorticoids in mast cells
title_full Transcriptomic data on the role of PEST-domain-enriched tyrosine phosphatase in the regulation of antigen-mediated activation and antiallergic action of glucocorticoids in mast cells
title_fullStr Transcriptomic data on the role of PEST-domain-enriched tyrosine phosphatase in the regulation of antigen-mediated activation and antiallergic action of glucocorticoids in mast cells
title_full_unstemmed Transcriptomic data on the role of PEST-domain-enriched tyrosine phosphatase in the regulation of antigen-mediated activation and antiallergic action of glucocorticoids in mast cells
title_short Transcriptomic data on the role of PEST-domain-enriched tyrosine phosphatase in the regulation of antigen-mediated activation and antiallergic action of glucocorticoids in mast cells
title_sort transcriptomic data on the role of pest-domain-enriched tyrosine phosphatase in the regulation of antigen-mediated activation and antiallergic action of glucocorticoids in mast cells
topic Energy
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143756/
https://www.ncbi.nlm.nih.gov/pubmed/30238026
http://dx.doi.org/10.1016/j.dib.2018.08.188
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