Genetic Engineering of Lactococcus lactis Co-producing Antigen and the Mucosal Adjuvant 3′ 5′- cyclic di Adenosine Monophosphate (c-di-AMP) as a Design Strategy to Develop a Mucosal Vaccine Prototype

Lactococcus lactis is a promising candidate for the development of mucosal vaccines. More than 20 years of experimental research supports this immunization approach. In addition, 3′ 5′- cyclic di-adenosine monophosphate (c-di-AMP) is a bacterial second messenger that plays a key role in the regulati...

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Detalles Bibliográficos
Autores principales: Quintana, Ingrid, Espariz, Martín, Villar, Silvina R., González, Florencia B., Pacini, Maria F., Cabrera, Gabriel, Bontempi, Iván, Prochetto, Estefanía, Stülke, Jörg, Perez, Ana R., Marcipar, Iván, Blancato, Victor, Magni, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143824/
https://www.ncbi.nlm.nih.gov/pubmed/30258417
http://dx.doi.org/10.3389/fmicb.2018.02100

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