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Nrf2-dependent antioxidant response mediated the protective effect of tanshinone IIA on doxorubicin-induced cardiotoxicity

Doxorubicin (DOX), a potent and widely used anticancer agent, can give rise to severe cardiotoxicity that limits its clinical use by inducing oxidative stress. Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is the central regulator of cellular responses to electrophilic/oxidative stress, which s...

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Detalles Bibliográficos
Autores principales:	Guo, Zhaohui, Yan, Miao, Chen, Lei, Fang, Pingfei, Li, Zhihua, Wan, Zimeng, Cao, Sisi, Hou, Zhenyan, Wei, Shanshan, Li, Wenqun, Zhang, Bikui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143869/ https://www.ncbi.nlm.nih.gov/pubmed/30233680 http://dx.doi.org/10.3892/etm.2018.6614

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