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Downregulation of MCT4 for lactate exchange promotes the cytotoxicity of NK cells in breast carcinoma
Monocarboxylate transporter‐4 (MCT4), a monocarboxylic acid transporter, demonstrates significantly increased expression in the majority of malignancies. We performed an experiment using BALB/C mice, and our results showed that ShMCT4 transfection or the pharmaceutic inhibition of MCT4 with 7acc1 st...
Autores principales: | Long, Yaping, Gao, Zihe, Hu, Xiao, Xiang, Feng, Wu, Zhaozhen, Zhang, Jiahui, Han, Xiao, Yin, Liyong, Qin, Junfang, Lan, Lan, Yin, Fuzai, Wang, Yue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143925/ https://www.ncbi.nlm.nih.gov/pubmed/30051648 http://dx.doi.org/10.1002/cam4.1713 |
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