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Targeting of AKT/ERK/CTNNB1 by DAW22 as a potential therapeutic compound for malignant peripheral nerve sheath tumor
Malignant peripheral nerve sheath tumors (MPNSTs) are an aggressive form of soft tissue neoplasm with extremely poor prognosis and no effective medical options currently available. MPNSTs can occur either sporadically or in association with the neurofibromatosis type 1 (NF1) syndrome. Importantly, a...
Autores principales: | Li, Xiao‐Xiao, Zhang, Shi‐Jie, Chiu, Amy P., Lo, Lilian H., Huang, Jian, Rowlands, Dewi K., Wang, Jinhui, Keng, Vincent W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144169/ https://www.ncbi.nlm.nih.gov/pubmed/30112810 http://dx.doi.org/10.1002/cam4.1732 |
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