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Targeting of AKT/ERK/CTNNB1 by DAW22 as a potential therapeutic compound for malignant peripheral nerve sheath tumor

Malignant peripheral nerve sheath tumors (MPNSTs) are an aggressive form of soft tissue neoplasm with extremely poor prognosis and no effective medical options currently available. MPNSTs can occur either sporadically or in association with the neurofibromatosis type 1 (NF1) syndrome. Importantly, a...

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Detalles Bibliográficos
Autores principales: Li, Xiao‐Xiao, Zhang, Shi‐Jie, Chiu, Amy P., Lo, Lilian H., Huang, Jian, Rowlands, Dewi K., Wang, Jinhui, Keng, Vincent W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144169/
https://www.ncbi.nlm.nih.gov/pubmed/30112810
http://dx.doi.org/10.1002/cam4.1732

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