Study protocol for the MEXiletine hydrochloride administration trial: a placebo-controlled, randomised, double-blind, multicentre, crossover study of its efficacy and safety in spinal and bulbar muscular atrophy (MEXPRESS)

INTRODUCTION: Spinal and bulbar muscular atrophy (SBMA) is a slowly progressive neuromuscular disease. Cold exposure often leads to worsening of motor symptoms including paresis. Although mexiletine hydrochloride administration has been shown to be effective for the treatment of several muscular dis...

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Detalles Bibliográficos
Autores principales: Yamada, Shinichiro, Hashizume, Atsushi, Hijikata, Yasuhiro, Inagaki, Tomonori, Ito, Daisuke, Kinoshita, Fumie, Nakatochi, Masahiro, Kobayashi, Yumiko, Hirakawa, Akihiro, Nakamura, Tomohiko, Katsuno, Masahisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144396/
https://www.ncbi.nlm.nih.gov/pubmed/30206090
http://dx.doi.org/10.1136/bmjopen-2018-023041

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