Cargando…
Single molecule kinetics uncover roles for E. coli RecQ DNA helicase domains and interaction with SSB
Most RecQ DNA helicases share a conserved domain arrangement that mediates their activities in genomic stability. This arrangement comprises a helicase motor domain, a RecQ C-terminal (RecQ-C) region including a winged-helix (WH) domain, and a ‘Helicase and RNase D C-terminal’ (HRDC) domain. Single-...
Autores principales: | Bagchi, Debjani, Manosas, Maria, Zhang, Weiting, Manthei, Kelly A, Hodeib, Samar, Ducos, Bertrand, Keck, James L, Croquette, Vincent |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144805/ https://www.ncbi.nlm.nih.gov/pubmed/30053104 http://dx.doi.org/10.1093/nar/gky647 |
Ejemplares similares
-
The RecQ helicase Sgs1 drives ATP-dependent disruption of Rad51 filaments
por: Crickard, J Brooks, et al.
Publicado: (2019) -
Nanopore tweezers measurements of RecQ conformational changes reveal the energy landscape of helicase motion
por: Craig, Jonathan M, et al.
Publicado: (2022) -
Active and passive mechanisms of helicases
por: Manosas, Maria, et al.
Publicado: (2010) -
Mechanism of RecQ helicase mechanoenzymatic coupling reveals that the DNA interactions of the ADP-bound enzyme control translocation run terminations
por: Sarlós, Kata, et al.
Publicado: (2015) -
Collaborative coupling between polymerase and helicase for leading-strand synthesis
por: Manosas, Maria, et al.
Publicado: (2012)