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Small synthetic molecule-stabilized RNA pseudoknot as an activator for –1 ribosomal frameshifting

Programmed –1 ribosomal frameshifting (−1PRF) is a recoding mechanism to make alternative proteins from a single mRNA transcript. −1PRF is stimulated by cis-acting signals in mRNA, a seven-nucleotide slippery sequence and a downstream secondary structure element, which is often a pseudoknot. In this...

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Detalles Bibliográficos
Autores principales:	Matsumoto, Saki, Caliskan, Neva, Rodnina, Marina V, Murata, Asako, Nakatani, Kazuhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144811/ https://www.ncbi.nlm.nih.gov/pubmed/30085309 http://dx.doi.org/10.1093/nar/gky689

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