SB Driver Analysis: a Sleeping Beauty cancer driver analysis framework for identifying and prioritizing experimentally actionable oncogenes and tumor suppressors

Cancer driver prioritization for functional analysis of potential actionable therapeutic targets is a significant challenge. Meta-analyses of mutated genes across different human cancer types for driver prioritization has reaffirmed the role of major players in cancer, including KRAS, TP53 and EGFR,...

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Detalles Bibliográficos
Autores principales: Newberg, Justin Y, Black, Michael A, Jenkins, Nancy A, Copeland, Neal G, Mann, Karen M, Mann, Michael B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144815/
https://www.ncbi.nlm.nih.gov/pubmed/29846651
http://dx.doi.org/10.1093/nar/gky450

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