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A novel λ integrase-mediated seamless vector transgenesis platform for therapeutic protein expression
Advances in stem cell engineering, gene therapy and molecular medicine often involve genome engineering at a cellular level. However, functionally large or multi transgene cassette insertion into the human genome still remains a challenge. Current practices such as random transgene integration or ta...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144826/ https://www.ncbi.nlm.nih.gov/pubmed/29893931 http://dx.doi.org/10.1093/nar/gky500 |