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A strongly pairing fifth base: oligonucleotides with a C-nucleoside replacing thymidine
There are five canonical bases in DNA and RNA. Each base has its particular molecular recognition properties and base pairing strength. Thymine and uracil form only two hydrogen bonds when pairing with adenine, and duplexes rich in A:T base pairs are more labile than duplexes rich in C and G, making...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144870/ https://www.ncbi.nlm.nih.gov/pubmed/30085103 http://dx.doi.org/10.1093/nar/gky669 |