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Cytotoxic chemotherapy reduces T cell trafficking to the spleen by downregulating the expression of C-C motif chemokine ligand 21 and C-C motif chemokine ligand 19

T cells serve an important role in the destruction of tumor cells and clearing of foreign pathogens. Previous studies have suggested that the T cell immune response of tumor-bearing patients is significantly lower than that of healthy people, and the principal reason for this is lymphocytopenia, whi...

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Detalles Bibliográficos
Autores principales: Liu, Lina, Zhao, Lintao, Yang, Yang, Gao, Jianbao, Hu, Chunyan, Guo, Bo, Zhu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144923/
https://www.ncbi.nlm.nih.gov/pubmed/30250567
http://dx.doi.org/10.3892/ol.2018.9287