Cargando…

High-throughput inference of pairwise coalescence times identifies signals of selection and enriched disease heritability

Interest in reconstructing demographic histories has motivated the development of methods to estimate locus-specific pairwise coalescence times from whole-genome sequence data. Here we introduce a powerful new method, ASMC, that can estimate coalescence times using only SNP array data, and is orders...

Descripción completa

Detalles Bibliográficos
Autores principales: Palamara, Pier Francesco, Terhorst, Jonathan, Song, Yun S., Price, Alkes L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145075/
https://www.ncbi.nlm.nih.gov/pubmed/30104759
http://dx.doi.org/10.1038/s41588-018-0177-x