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High-throughput inference of pairwise coalescence times identifies signals of selection and enriched disease heritability
Interest in reconstructing demographic histories has motivated the development of methods to estimate locus-specific pairwise coalescence times from whole-genome sequence data. Here we introduce a powerful new method, ASMC, that can estimate coalescence times using only SNP array data, and is orders...
Autores principales: | Palamara, Pier Francesco, Terhorst, Jonathan, Song, Yun S., Price, Alkes L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145075/ https://www.ncbi.nlm.nih.gov/pubmed/30104759 http://dx.doi.org/10.1038/s41588-018-0177-x |
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