Cargando…

Over-expressed microRNA-181a reduces glomerular sclerosis and renal tubular epithelial injury in rats with chronic kidney disease via down-regulation of the TLR/NF-κB pathway by binding to CRY1

BACKGROUND: MicroRNAs (miRNAs) contribute to the progression of chronic kidney disease (CKD) by regulating renal homeostasis. This study explored the effects of miR-181a on CKD through the Toll-like receptor (TLR)/nuclear factor-kappa B (NF-κB) pathway by binding to CRY1. METHODS: Seventy male rats...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Lei, Pang, Xin-Lu, Shang, Wen-Jun, Xie, Hong-Chang, Wang, Jun-Xiang, Feng, Gui-Wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145098/ https://www.ncbi.nlm.nih.gov/pubmed/30241461 http://dx.doi.org/10.1186/s10020-018-0045-2

Ejemplares similares

TLR4/NF-κB Signaling Induces GSDMD-Related Pyroptosis in Tubular Cells in Diabetic Kidney Disease
por: Wang, Youliang, et al.
Publicado: (2019)

MALAT1 promotes liver fibrosis by sponging miR-181a and activating TLR4-NF-κB signaling
por: Wang, Yinghui, et al.
Publicado: (2021)

Baicalein alleviates tubular-interstitial nephritis in vivo and in vitro by down-regulating NF-κB and MAPK pathways
por: Chen, Yan, et al.
Publicado: (2018)

Salvianolic Acid B Attenuates Iopromide-Induced Renal Tubular Epithelial Cell Injury by Inhibiting the TLR4/NF-κB/NLRP3 Signaling Pathway
por: Pei, Ming Xin, et al.
Publicado: (2022)

Atorvastatin reduces contrast media-induced pyroptosis of renal tubular epithelial cells by inhibiting the TLR4/MyD88/NF-κB signaling pathway
por: Yue, Rong-zheng, et al.
Publicado: (2023)

Chlamydia abortus Pmp18.1 Induces IL-1β Secretion by TLR4 Activation through the MyD88, NF-κB, and Caspase-1 Signaling Pathways
por: Pan, Qing, et al.
Publicado: (2017)

Berberine ameliorates diabetic nephropathy by inhibiting TLR4/NF-κB pathway
por: Zhu, Liping, et al.
Publicado: (2018)

Mechanisms of Glomerular Albumin Filtration and Tubular Reabsorption
por: Tojo, Akihiro, et al.
Publicado: (2012)

Glomerular and Tubular Functions in Transfusion-Dependent Thalassemia
por: Sookaromdee, Pathum, et al.
Publicado: (2018)

Epimedium sagittatum inhibits TLR4/MD-2 mediated NF-κB signaling pathway with anti-inflammatory activity
por: Yan, Ni, et al.
Publicado: (2018)

Uric Acid Induces Renal Inflammation via Activating Tubular NF-κB Signaling Pathway
por: Zhou, Yang, et al.
Publicado: (2012)

Afferent arteriolopathy and glomerular collapse but not segmental sclerosis induce tubular atrophy in old spontaneously hypertensive rats
por: Leh, Sabine, et al.
Publicado: (2011)

NF-κB, JNK, and TLR Signaling Pathways in Hepatocarcinogenesis
por: Maeda, Shin
Publicado: (2010)

Roles of TLR7 in Activation of NF-κB Signaling of Keratinocytes by Imiquimod
por: Li, Zheng Jun, et al.
Publicado: (2013)

NF-κB Pathways in the Pathogenesis of Multiple Sclerosis and the Therapeutic Implications
por: Leibowitz, Saskia M., et al.
Publicado: (2016)

Importance of extra- and intracellular domains of TLR1 and TLR2 in NFκB signaling
por: Sandor, Frantisek, et al.
Publicado: (2003)

Glomerular and Tubular Damage Markers Are Elevated in Patients With Diabetes
por: Nauta, Ferdau L., et al.
Publicado: (2011)

Tubular and Glomerular Injury in Diabetes and the Impact of ACE Inhibition
por: Nielsen, Stine E., et al.
Publicado: (2009)

Renal markers for assessment of renal tubular and glomerular dysfunction
por: Spasovski, Dejan
Publicado: (2013)

Glomerular podocyte dysfunction in inherited renal tubular disease
por: Huang, Li-Min, et al.
Publicado: (2021)

Effects of Curcumin on High Glucose-Induced Epithelial-to-Mesenchymal Transition in Renal Tubular Epithelial Cells Through the TLR4-NF-κB Signaling Pathway
por: Liu, Xinhui, et al.
Publicado: (2021)

Celastrol ameliorates osteoarthritis via regulating TLR2/NF-κB signaling pathway
por: Yang, Guangxia, et al.
Publicado: (2022)

Vinpocetine alleviate cerebral ischemia/reperfusion injury by down-regulating TLR4/MyD88/NF-κB signaling
por: Wu, Li-Rong, et al.
Publicado: (2017)

MicroRNA-451 inhibits inflammation and proliferation of glomerular mesangial cells through down-regulating PSMD11 and NF-κB p65
por: Wei, Hua, et al.
Publicado: (2019)

The roles of the TLR/NF-κB signaling pathway in the mutual interactions between the lung and the large intestine
por: Fu, Wen, et al.
Publicado: (2018)

Proximal Tubular Hypertrophy and Enlarged Glomerular and Proximal Tubular Urinary Space in Obese Subjects with Proteinuria
por: Tobar, Ana, et al.
Publicado: (2013)

Modulation of TLR4/NFκB Pathways in Autoimmune Myocarditis
por: Interdonato, Livia, et al.
Publicado: (2023)

LIGHT Amplification by NF-κB Contributes to TLR3 Signaling Pathway-Induced Acute Hepatitis
por: Lai, Dongming, et al.
Publicado: (2023)

Etiopathology of chronic tubular, glomerular and renovascular nephropathies: Clinical implications
por: López-Novoa, José M, et al.
Publicado: (2011)

Acute Tubular Necrosis and Renal Failure in Patients with Glomerular Disease
por: Tavares, Maria Brandão, et al.
Publicado: (2012)

Glomerular and Tubular Functions in Children and Adults with Transfusion-Dependent Thalassemia
por: Annayev, Agageldi, et al.
Publicado: (2018)

Using random forest algorithm for glomerular and tubular injury diagnosis
por: Song, Wenzhu, et al.
Publicado: (2022)

Renal glomerular and tubular responses to glutaraldehyde- polymerized human hemoglobin
por: Williams, Matthew C., et al.
Publicado: (2023)

Effect of β-patchoulene on cerebral ischemia-reperfusion injury and the TLR4/NF-κB signaling pathway
por: Zhang, Fu-Bo, et al.
Publicado: (2019)

Expression of TLR4-MyD88 and NF-κB in the Iris during Endotoxin-Induced Uveitis
por: Li, Shang, et al.
Publicado: (2010)

SOCS2 overexpression alleviates diabetic nephropathy in rats by inhibiting the TLR4/NF-κB pathway
por: Yang, Suxia, et al.
Publicado: (2017)

Serum NF-κBp65, TLR4 as Biomarker for Diagnosis of Preeclampsia
por: Litang, Zhao, et al.
Publicado: (2017)

Cofilin1 is involved in hypertension-induced renal damage via the regulation of NF-κB in renal tubular epithelial cells
por: Wang, Quan-zhen, et al.
Publicado: (2015)

ANTI-INFLAMMATORY ACTIVITY OF PLATYCODIN D ON ALCOHOL-INDUCED FATTY LIVER RATS VIA TLR4-MYD88-NF-κB SIGNAL PATH
por: Wu, Jing-tao, et al.
Publicado: (2016)

Lipopolysaccharide promotes lipid accumulation in human adventitial fibroblasts via TLR4-NF-κB pathway
por: Wang, Jun, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_sp58rmv9l9rkjo9kvj2abb4m6m