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Over-expressed microRNA-181a reduces glomerular sclerosis and renal tubular epithelial injury in rats with chronic kidney disease via down-regulation of the TLR/NF-κB pathway by binding to CRY1

BACKGROUND: MicroRNAs (miRNAs) contribute to the progression of chronic kidney disease (CKD) by regulating renal homeostasis. This study explored the effects of miR-181a on CKD through the Toll-like receptor (TLR)/nuclear factor-kappa B (NF-κB) pathway by binding to CRY1. METHODS: Seventy male rats...

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Detalles Bibliográficos
Autores principales:	Liu, Lei, Pang, Xin-Lu, Shang, Wen-Jun, Xie, Hong-Chang, Wang, Jun-Xiang, Feng, Gui-Wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145098/ https://www.ncbi.nlm.nih.gov/pubmed/30241461 http://dx.doi.org/10.1186/s10020-018-0045-2

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