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Comparative mechanical analysis of deep brain stimulation electrodes
The new field of neuro-prosthetics focuses on the design and implementation of neural prostheses to restore some of the lost neural functions. The electrode-tissue contacts remain one of the major obstacles of neural prostheses microstructure. Recently, Microelectrode fabrication techniques have bee...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145105/ https://www.ncbi.nlm.nih.gov/pubmed/30227862 http://dx.doi.org/10.1186/s12938-018-0557-6 |
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author | Draz, H. H. Gabran, S. R. I. Basha, Mohamed Mostafa, Hassan Abu-Elyazeed, Mohamed F. Zaki, Amal |
author_facet | Draz, H. H. Gabran, S. R. I. Basha, Mohamed Mostafa, Hassan Abu-Elyazeed, Mohamed F. Zaki, Amal |
author_sort | Draz, H. H. |
collection | PubMed |
description | The new field of neuro-prosthetics focuses on the design and implementation of neural prostheses to restore some of the lost neural functions. The electrode-tissue contacts remain one of the major obstacles of neural prostheses microstructure. Recently, Microelectrode fabrication techniques have been developed to have a long-term and stable interface with the brain. In this paper, a comparative analysis of finite element models (FEM) for several electrode layouts is conducted. FEM involves parametric and sensitivity analysis to show the effects of the different design parameters on the electrode mechanical performance. These parameters include electrode dimensions, geometry, and materials. The electrodes mechanical performance is evaluated with various analysis techniques including: linear buckling analysis, stationary analysis with axial and shear loading, and failure analysis for brittle and ductile materials. Finally, a novel figure of merit (FOM) is presented and dedicated to the various electrodes prototypes. The proposed designs take into account mechanical performance, fabrication cost, and cross sectional area of the electrode. The FOM provides important design insights to help the electrodes designers to select the best electrode design parameters that meet their design constraints. |
format | Online Article Text |
id | pubmed-6145105 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-61451052018-09-24 Comparative mechanical analysis of deep brain stimulation electrodes Draz, H. H. Gabran, S. R. I. Basha, Mohamed Mostafa, Hassan Abu-Elyazeed, Mohamed F. Zaki, Amal Biomed Eng Online Review The new field of neuro-prosthetics focuses on the design and implementation of neural prostheses to restore some of the lost neural functions. The electrode-tissue contacts remain one of the major obstacles of neural prostheses microstructure. Recently, Microelectrode fabrication techniques have been developed to have a long-term and stable interface with the brain. In this paper, a comparative analysis of finite element models (FEM) for several electrode layouts is conducted. FEM involves parametric and sensitivity analysis to show the effects of the different design parameters on the electrode mechanical performance. These parameters include electrode dimensions, geometry, and materials. The electrodes mechanical performance is evaluated with various analysis techniques including: linear buckling analysis, stationary analysis with axial and shear loading, and failure analysis for brittle and ductile materials. Finally, a novel figure of merit (FOM) is presented and dedicated to the various electrodes prototypes. The proposed designs take into account mechanical performance, fabrication cost, and cross sectional area of the electrode. The FOM provides important design insights to help the electrodes designers to select the best electrode design parameters that meet their design constraints. BioMed Central 2018-09-18 /pmc/articles/PMC6145105/ /pubmed/30227862 http://dx.doi.org/10.1186/s12938-018-0557-6 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Review Draz, H. H. Gabran, S. R. I. Basha, Mohamed Mostafa, Hassan Abu-Elyazeed, Mohamed F. Zaki, Amal Comparative mechanical analysis of deep brain stimulation electrodes |
title | Comparative mechanical analysis of deep brain stimulation electrodes |
title_full | Comparative mechanical analysis of deep brain stimulation electrodes |
title_fullStr | Comparative mechanical analysis of deep brain stimulation electrodes |
title_full_unstemmed | Comparative mechanical analysis of deep brain stimulation electrodes |
title_short | Comparative mechanical analysis of deep brain stimulation electrodes |
title_sort | comparative mechanical analysis of deep brain stimulation electrodes |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145105/ https://www.ncbi.nlm.nih.gov/pubmed/30227862 http://dx.doi.org/10.1186/s12938-018-0557-6 |
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