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Establishing a stable, repeatable platform for measuring changes in sperm DNA methylation
BACKGROUND: Several independent research groups have shown that alterations in human sperm methylation profiles correlate with decreased fecundity and an increased risk of poor embryo development. Moving these initial findings from the lab into a clinical setting where they can be used to measure ma...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145208/ https://www.ncbi.nlm.nih.gov/pubmed/30227883 http://dx.doi.org/10.1186/s13148-018-0551-7 |