Development of a new patient-derived xenograft humanised mouse model to study human-specific tumour microenvironment and immunotherapy

OBJECTIVE: As the current therapeutic strategies for human hepatocellular carcinoma (HCC) have been proven to have limited effectiveness, immunotherapy becomes a compelling way to tackle the disease. We aim to provide humanised mouse (humice) models for the understanding of the interaction between h...

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Detalles Bibliográficos
Autores principales: Zhao, Yue, Shuen, Timothy Wai Ho, Toh, Tan Boon, Chan, Xue Ying, Liu, Min, Tan, Sue Yee, Fan, Yong, Yang, Hechuan, Lyer, Shridhar Ganpathi, Bonney, Glenn Kunnath, Loh, Eva, Chang, Kenneth Tou En, Tan, Thiam Chye, Zhai, Weiwei, Chan, Jerry Kok Yen, Chow, Edward Kai-Hua, Chee, Cheng Ean, Lee, Guan Huei, Dan, Yock Young, Chow, Pierce Kah-Hoe, Toh, Han Chong, Lim, Seng Gee, Chen, Qingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
GI cancer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145285/
https://www.ncbi.nlm.nih.gov/pubmed/29602780
http://dx.doi.org/10.1136/gutjnl-2017-315201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145285/
https://www.ncbi.nlm.nih.gov/pubmed/29602780
http://dx.doi.org/10.1136/gutjnl-2017-315201

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