Efficient and tumor-specific knockdown of MTDH gene attenuates paclitaxel resistance of breast cancer cells both in vivo and in vitro

BACKGROUND: Drug resistance of paclitaxel (TAX), the first-line chemotherapy drug for breast cancer, was reported to develop in 90% of patients with breast cancer, especially metastatic breast cancer. Investigating the mechanism of TAX resistance of breast cancer cells and developing the strategy im...

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Detalles Bibliográficos
Autores principales: Yang, Liu, Tian, Yanhua, Leong, Wei Sun, Song, Heng, Yang, Wei, Wang, Meiqi, Wang, Xinle, Kong, Jing, Shan, Baoen, Song, Zhengchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145322/
https://www.ncbi.nlm.nih.gov/pubmed/30227879
http://dx.doi.org/10.1186/s13058-018-1042-7

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