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Imaging-based clusters in current smokers of the COPD cohort associate with clinical characteristics: the SubPopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS)

BACKGROUND: Classification of COPD is usually based on the severity of airflow, which may not sensitively differentiate subpopulations. Using a multiscale imaging-based cluster analysis (MICA), we aim to identify subpopulations for current smokers with COPD. METHODS: Among the SPIROMICS subjects, we...

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Detalles Bibliográficos
Autores principales: Haghighi, Babak, Choi, Sanghun, Choi, Jiwoong, Hoffman, Eric A., Comellas, Alejandro P., Newell, John D., Graham Barr, R., Bleecker, Eugene, Cooper, Christopher B., Couper, David, Han, Mei Lan, Hansel, Nadia N., Kanner, Richard E., Kazerooni, Ella A., Kleerup, Eric A. C., Martinez, Fernando J., O’Neal, Wanda, Rennard, Stephen I., Woodruff, Prescott G., Lin, Ching-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145340/
https://www.ncbi.nlm.nih.gov/pubmed/30227877
http://dx.doi.org/10.1186/s12931-018-0888-7