Exploitation of novel wild type solventogenic strains for butanol production

Butanol has been regarded as an important bulk chemical and advanced biofuel; however, large scaling butanol production by solventogenic Clostridium sp. is still not economically feasible due to the high cost of substrates, low butanol titer and yield caused by the toxicity of butanol and formation...

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Autores principales: Xin, Fengxue, Yan, Wei, Zhou, Jie, Wu, Hao, Dong, Weiliang, Ma, Jiangfeng, Zhang, Wenming, Jiang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145368/
https://www.ncbi.nlm.nih.gov/pubmed/30250504
http://dx.doi.org/10.1186/s13068-018-1252-3
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author Xin, Fengxue
Yan, Wei
Zhou, Jie
Wu, Hao
Dong, Weiliang
Ma, Jiangfeng
Zhang, Wenming
Jiang, Min
author_facet Xin, Fengxue
Yan, Wei
Zhou, Jie
Wu, Hao
Dong, Weiliang
Ma, Jiangfeng
Zhang, Wenming
Jiang, Min
author_sort Xin, Fengxue
collection PubMed
description Butanol has been regarded as an important bulk chemical and advanced biofuel; however, large scaling butanol production by solventogenic Clostridium sp. is still not economically feasible due to the high cost of substrates, low butanol titer and yield caused by the toxicity of butanol and formation of by-products. Renewed interests in biobutanol as biofuel and rapid development in genetic tools have spurred technological advances to strain modifications. Comprehensive reviews regarding these aspects have been reported elsewhere in detail. Meanwhile, more wild type butanol producers with unique properties were also isolated and characterized. However, few reviews addressed these discoveries of novel wild type solventogenic Clostridium sp. strains. Accordingly, this review aims to comprehensively summarize the most recent advances on wild type butanol producers in terms of fermentation patterns, substrate utilization et al. Future perspectives using these native ones as chassis for genetic modification were also discussed.
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spelling pubmed-61453682018-09-24 Exploitation of novel wild type solventogenic strains for butanol production Xin, Fengxue Yan, Wei Zhou, Jie Wu, Hao Dong, Weiliang Ma, Jiangfeng Zhang, Wenming Jiang, Min Biotechnol Biofuels Review Butanol has been regarded as an important bulk chemical and advanced biofuel; however, large scaling butanol production by solventogenic Clostridium sp. is still not economically feasible due to the high cost of substrates, low butanol titer and yield caused by the toxicity of butanol and formation of by-products. Renewed interests in biobutanol as biofuel and rapid development in genetic tools have spurred technological advances to strain modifications. Comprehensive reviews regarding these aspects have been reported elsewhere in detail. Meanwhile, more wild type butanol producers with unique properties were also isolated and characterized. However, few reviews addressed these discoveries of novel wild type solventogenic Clostridium sp. strains. Accordingly, this review aims to comprehensively summarize the most recent advances on wild type butanol producers in terms of fermentation patterns, substrate utilization et al. Future perspectives using these native ones as chassis for genetic modification were also discussed. BioMed Central 2018-09-18 /pmc/articles/PMC6145368/ /pubmed/30250504 http://dx.doi.org/10.1186/s13068-018-1252-3 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Xin, Fengxue
Yan, Wei
Zhou, Jie
Wu, Hao
Dong, Weiliang
Ma, Jiangfeng
Zhang, Wenming
Jiang, Min
Exploitation of novel wild type solventogenic strains for butanol production
title Exploitation of novel wild type solventogenic strains for butanol production
title_full Exploitation of novel wild type solventogenic strains for butanol production
title_fullStr Exploitation of novel wild type solventogenic strains for butanol production
title_full_unstemmed Exploitation of novel wild type solventogenic strains for butanol production
title_short Exploitation of novel wild type solventogenic strains for butanol production
title_sort exploitation of novel wild type solventogenic strains for butanol production
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145368/
https://www.ncbi.nlm.nih.gov/pubmed/30250504
http://dx.doi.org/10.1186/s13068-018-1252-3
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