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Time course of focused ultrasound effects on β-amyloid plaque pathology in the TgCRND8 mouse model of Alzheimer’s disease
Previous studies have demonstrated that temporarily increasing the permeability of the blood-brain barrier using focused ultrasound can reduce β-amyloid plaque load and improve cognitive function in animal models of Alzheimer’s disease. However, the underlying mechanism and duration for which the ef...
Autores principales: | Poon, Charissa T., Shah, Kairavi, Lin, Chiungting, Tse, Ryan, Kim, Kate K., Mooney, Skyler, Aubert, Isabelle, Stefanovic, Bojana, Hynynen, Kullervo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145880/ https://www.ncbi.nlm.nih.gov/pubmed/30232364 http://dx.doi.org/10.1038/s41598-018-32250-3 |
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